Fecal Transplantation Essay

Transplantation

Transplantation is the process where a living tissue (graft) is transferred from one section to another part of the body, or from one person to another. Theoretically, transplantation can be for any tissue or organ. Where surgical and medical procedures are insufficient transplantation becomes the solution. This paper emphasizes on fecal microbiota transplantation.

Fecal Microbiota Transplantation

This type of transplantation involves the collection of stool from a healthy person, the placing it in the patient’s intestines (Moos et al., 2016). Application of antibiotics sometimes suppresses or kills essential bacteria, leading to accumulation of Clostridium difficile (C. diff) in the colon. The infection causes C. diff colitis that may end up with fatal diarrhea. Hence, transplantation is the best way to replace good bacteria (Smits et al., 2016).

Procedure

Two days to the scheme, on the patient, he or she stops taking antibiotics and placed on a liquid diet. On the night before the patient conducts laxative preparation and his or her allergic reactions noted. To the donor side before transplantation, screening by the physician for infectious agents through stool and blood tests. Colonoscopy is the standard procedure. The colonoscope, during the process, is pushed through the colon, then extracted and the fecal matter from the donor is delivered to the colon of the patient (Jacob et al., 2017). Transplantation can sometimes have side effects such as cramping, bloating, diarrhea or constipation and abdominal discomfort. According to Cammarota et al. (2017), more research should be done on the procedure to come up with remedies on disorders, for example, inflammatory bowel defect.

Conclusion

Fecal microbiota transplantation is an effective procedure. Also, it is cheap and has fewer risks. Researchers should conduct more studies on fecal microbiota transplantation to find its additional benefits on medicine.

References

Cammarota, G., Ianiro, G., Tilg, H., Rajilić-Stojanović, M., Kump, P., Satokari, R., & Segal, J. (2017). European consensus conference on fecal microbiota transplantation in clinical practice. Gut, gutjnl-2016.

Jacob, V., Crawford, C., Cohen-Mekelburg, S., Schneider, Y., Chabouni, F., O’Neil, S., Bosworth, B., Longman, R. (2017). P-118 Fecal Microbiota Transplantation via Colonoscopy is safe and Effective in Active Ulcerative Colitis. (Inflammatory bowel diseases.)

Moos, W. H., Faller, D. V., Harpp, D. N., Kanara, I., Pernokas, J., Powers, W. R., & Steliou, K. (2016). Microbiota and neurological disorders: a gut feeling. BioResearch open access, 5(1), 137-145.

Smits, W. K., Lyras, D., Lacy, D. B., Wilcox, M. H., & Kuijper, E. J. (2016). Clostridium difficile infection. Nature Reviews Disease Primers, 2, 16020.